Clene’s Lead Amyotrophic Lateral Sclerosis shows improved function,…

Clene’s Lead Amyotrophic Lateral Sclerosis shows improved function,…

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  • Clene Inc CLNN announced new results shows obtained ALS Patient Function Score (ALSFRS-R) and Delayed Time to Clinical Worsening from the most recent 12-month data cut-off of the open-label extension (OLE) of the Phase 2 RESCUE ALS study in people with early amyotrophic lateral sclerosis ( ALS) treated with CNM-Au8.
  • CNM-Au8 preserved physical function when administered for 48 weeks as measured by the ALSFRS-R, a clinical assessment measuring activities such as walking, speaking, breathing, feeding and independent dressing.
  • Related: Clene shares rise on encouraging data from multiple sclerosis candidates.
  • Significant functional survival (ALSFRS-R) was observed from randomization to 48 weeks, with significant functional survival during the open-label long-term extension week (OLE) from 24 to 120 weeks after randomization.
  • Significantly reduced risk of clinical worsening of ALS by 52% over 120 weeks.
  • CNM-Au8 treatment was well tolerated with no long-term safety concerns.
  • Price promotion: CLNN shares are up 4.17% to $1.25 on Monday’s latest check.

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