Pardes Biosciences looks for alternatives after failed COVID-19 study…

Pardes Biosciences looks for alternatives after failed COVID-19 study…

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  • Pardes Biosciences Inc PRDS reported topline Results from its Phase 2 clinical trial evaluating pomotrelvir (formerly PBI-0451) for mild to moderate COVID-19 in vaccinated adults with no risk factors for developing severe disease.
  • Pomotrelvir did not meet the primary endpoint of the proportion of participants undetectable for infectious SARS-CoV-2 on day 3 of treatment with pomotrelvir compared to placebo.
  • 70% achieved undetectable levels in the pomotrelvir-treated group versus 63% in the placebo group (p=0.57).
  • Otherwise, rapid clearance of SARS-CoV-2 virus and rapid relief of targeted and important COVID-19 symptoms occurred in healthy, vaccinated adults with no risk factors for progression to serious disease, regardless of the treatment arm.
  • The company will suspend further development of pomotrelvir and review a number of strategic alternatives.
  • As of March 31, 2023, the Company’s preliminary cash, cash equivalents and short-term investments totaled approximately $172.4 million, which is sufficient to fund the Company’s operations next twelve months.
  • Price promotion: PRDS shares are up 6.82% to $1.41 on the latest check Monday.

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